Cytoreductive nephrectomy in the current treatment algorithm
نویسندگان
چکیده
منابع مشابه
Cytoreductive nephrectomy for metastatic renal cell carcinoma.
The incidence of renal cell carcinoma is increasing, with up to one-third of patients presenting with metastatic disease. Combination therapy is used to prolong survival in patients with metastatic renal cell carcinoma, which carries a poor prognosis. Although two pivotal phase 3 trials have demonstrated the efficacy of immunotherapy after cytoreductive nephrectomy for metastatic disease, for n...
متن کاملHypoalbuminaemia is associated with mortality in patients undergoing cytoreductive nephrectomy.
OBJECTIVE To evaluate whether poor nutrition is associated with mortality in patients undergoing cytoreductive nephrectomy (CN) for metastatic renal cell carcinoma (mRCC). PATIENTS AND METHODS A multi-institutional review of prospective databases identified 246 patients meeting inclusion criteria who underwent CN for mRCC from 1993 to 2012. Nutritional markers evaluated were: body mass index ...
متن کاملCytoreductive nephrectomy vs medical therapy as initial treatment: a rational approach to the sequence question in metastatic renal cell carcinoma.
BACKGROUND Renal cell carcinoma (RCC) can be considered as two distinct entities: localized and metastatic disease. METHODS We conducted a review of the scientific literature published within the past decade pertaining to cytoreductive nephrectomy for metastatic RCC. RESULTS Retrospective data and historical prospective series have demonstrated the survival benefit of debulking nephrectomy ...
متن کاملRole of cytoreductive nephrectomy in the targeted therapy era: A systematic review and meta-analysis
Purpose To determine the effectiveness and harm of cytoreductive nephrectomy versus no intervention in patients with metastatic renal carcinoma who undergo targeted therapy to improve overall survival. Materials and Methods A search strategy was conducted in the MEDLINE, CENTRAL, Embase, HTA, DARE, NHS, and LILACS databases. Searches were also conducted for unpublished literature through refe...
متن کاملLaparoscopic partial nephrectomy: current status.
OBJECTIVE Increasingly nephro-sparing partial nephrectomy has became widely accepted as a preferred treatment option for the select patient when the adenocarcinoma involves a solitary kidney or poorly functioning contralateral kidney, and in patients with synchronous bilateral tumors. While open partial nephrectomy is currently the standard nephron sparing procedure for treatment of renal tumor...
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ژورنال
عنوان ژورنال: Therapeutic Advances in Medical Oncology
سال: 2019
ISSN: 1758-8359,1758-8359
DOI: 10.1177/1758835919879026